Curcumin Compound to Treat Infection in Cattles

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    Context

    • In a major breakthrough in creating immunity in cattle against infectious diseases including mastitis, researchers have successfully validated the immunomodulation ability of a natural phytochemical compound with curcumin as the active ingredient.
      • Mastitis is an infectious disease condition resulting in an inflammatory reaction in the mammary gland of the cow.

    What is Curcumin?

    • It is a yellow pigment found primarily in turmeric. It is a polyphenol with anti-inflammatory properties and the ability to increase the amount of antioxidants that the body produces.
    • Research revealed that Curcumin offers immunity in dairy cattle against infectious diseases including mastitis by increasing complementary protein, Interferon, Immunoglobulin (IgM), lymphocytes and monocytes.
    • The compound will create appropriate immunity and facilitate increased milk production by 10 percent.

    Significance

    • The economic loss due to mastitis in India exceeds ?13,000 crore annually. 
    • No vaccination is available against mastitis. 
    • Antibiotics have been used to manage various infections in cattle. However, it has been noticed that the uncontrolled use of antibiotics results in increased antibiotic resistance. 
    • The irrational use of antibiotics for treating mastitis resulted in inter-species and inter-genus transfer of antibiotic resistance and creation of various multi-drug resistant microorganisms in the environment, which affects immunity of livestock and human health.

    Source: TH