{"id":59224,"date":"2025-11-15T18:45:41","date_gmt":"2025-11-15T13:15:41","guid":{"rendered":"https:\/\/www.nextias.com\/ca\/?p=59224"},"modified":"2025-11-17T12:55:58","modified_gmt":"2025-11-17T07:25:58","slug":"stem-cell-therapy","status":"publish","type":"post","link":"https:\/\/www.nextias.com\/ca\/current-affairs\/15-11-2025\/stem-cell-therapy","title":{"rendered":"STEM Cell Therapy"},"content":{"rendered":"\n<p><strong>Syllabus: GS3\/ Science &amp; Technology<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>In News<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Researchers at Osaka Metropolitan University have developed a new technique to heal spinal fractures using <strong>adipose-derived stem cells (ADSCs)<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>About<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Osteoporosis affects 15 million people in Japan and is rising globally with ageing populations.<\/li>\n\n\n\n<li>Vertebral compression fractures are the most common osteoporosis-related injuries.<\/li>\n\n\n\n<li>Current treatments (vertebroplasty, kyphoplasty, implants) have limitations: invasive, costly, risk of complications or re-fracture.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Stem cells<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Stem cells are undifferentiated biological cells capable of both self-renewal and differentiation into specialized cell types. They form the foundation of regenerative medicine and hold potential for treating degenerative, genetic, and injury-related diseases.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Types of Stem Cells<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Embryonic Stem Cells (ESCs):<\/strong>\n<ul class=\"wp-block-list\">\n<li>Pluripotent in nature; can form all cell types of the body.<\/li>\n\n\n\n<li>Derived from early-stage embryos.<\/li>\n\n\n\n<li>Pose ethical concerns due to their origin, leading to strict regulatory controls.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Adult (Somatic) Stem Cells:<\/strong>\n<ul class=\"wp-block-list\">\n<li>Multipotent, with limited capacity to differentiate compared to ESCs.<\/li>\n\n\n\n<li>Found in bone marrow, skin, adipose tissue, and other organs.<\/li>\n\n\n\n<li>Primarily responsible for maintaining and repairing tissue in which they are found.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Induced Pluripotent Stem Cells (iPSCs):\u00a0<\/strong>\n<ul class=\"wp-block-list\">\n<li>Created by reprogramming adult cells (like skin cells) to behave like pluripotent stem cells.<\/li>\n\n\n\n<li>Have similar properties to ESCs but without ethical issues.<\/li>\n\n\n\n<li>Useful in disease modeling, drug testing, and regenerative research.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Mesenchymal Stem Cells (MSCs):<\/strong><\/li>\n\n\n\n<li>A subset of adult stem cells found in bone marrow, adipose tissue, and the umbilical cord.<\/li>\n\n\n\n<li>Can differentiate into bone, cartilage, and fat cells.<\/li>\n\n\n\n<li>Widely studied for their role in bone and tissue regeneration.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Adipose-Derived Stem Cells (ADSCs)<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Adipose-derived stem cells are multipotent cells extracted from body fat. They are easy to harvest, even in elderly patients, and present a less invasive alternative to bone marrow stem cells.\u00a0<\/li>\n\n\n\n<li>Because of their high proliferation rate, ADSCs show strong potential for applications in bone, cartilage, and wound healing therapies.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Benefits of ADSC-Based Therapy<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Minimally invasive, as fat extraction is safer than bone marrow procedures.<\/li>\n\n\n\n<li>Effective even in older individuals with declining tissue quality.<\/li>\n\n\n\n<li>Promotes natural healing by activating repair-related genes.<\/li>\n\n\n\n<li>Reduces the need for synthetic implants or metallic hardware.<\/li>\n\n\n\n<li>Offers potential long-term cost savings by reducing repeat surgical interventions.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Concerns and Challenges<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Most studies are still at the animal-trial stage and human clinical trials are still ongoing.<\/li>\n\n\n\n<li>Long-term safety, stability, and risk of uncontrolled cell growth remain uncertain.<\/li>\n<\/ul>\n\n\n\n<p><strong>Source: TH<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>In News<\/strong><\/p>\n<li class=\"ms-5\">Researchers at Osaka Metropolitan University have developed a new technique to heal spinal fractures using adipose-derived stem cells (ADSCs).<\/li>\n<p><\/p>\n<p><strong>About<\/strong><\/p>\n<li class=\"ms-5\">Osteoporosis affects 15 million people in Japan and is rising globally with ageing populations.<\/li>\n<li class=\"ms-5\">Vertebral compression fractures are the most common osteoporosis-related injuries.<\/li>\n<li class=\"ms-5\">Current treatments (vertebroplasty, kyphoplasty, implants) have limitations: invasive, costly, risk of complications or re-fracture.<\/li>\n<p><a href=\"https:\/\/www.nextias.com\/ca\/current-affairs\/15-11-2025\/stem-cell-therapy\" class=\"btn btn-primary btn-sm float-end\">Read\u00a0More<\/a><\/p>\n","protected":false},"author":15,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[21],"tags":[],"class_list":["post-59224","post","type-post","status-publish","format-standard","hentry","category-current-affairs"],"acf":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/59224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/comments?post=59224"}],"version-history":[{"count":2,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/59224\/revisions"}],"predecessor-version":[{"id":59245,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/59224\/revisions\/59245"}],"wp:attachment":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/media?parent=59224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/categories?post=59224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/tags?post=59224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}