{"id":28867,"date":"2024-09-03T18:27:27","date_gmt":"2024-09-03T12:57:27","guid":{"rendered":"https:\/\/www.nextias.com\/ca\/?p=28867"},"modified":"2024-09-03T18:27:29","modified_gmt":"2024-09-03T12:57:29","slug":"mitochondrial-treatment-for-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/www.nextias.com\/ca\/current-affairs\/03-09-2024\/mitochondrial-treatment-for-parkinsons-disease","title":{"rendered":"Mitochondrial Treatment for Parkinson\u2019s Disease"},"content":{"rendered":"\n<p><strong>Syllabus: GS2\/Health<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Context<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Recent research has identified a key protein that could <strong>lead to new treatments for Parkinson\u2019s disease and other brain conditions.<\/strong><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>About<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Researchers who studyParkinson\u2019s disease have been investigating<strong> the role that mitochondria<\/strong> \u2013 the powerhouses that fuel cells \u2013 play in Parkinson\u2019s.<\/li>\n\n\n\n<li>Researchers have identified<strong> a key protein <\/strong>that could lead to new treatments for Parkinson\u2019s disease and other brain conditions.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Mitochondrial Dynamics and Neurodegeneration<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Emerging studies have linked <strong>imbalances in mitochondrial processes<\/strong> to different neurodegenerative diseases, including Parkinson\u2019s disease.\n<ul class=\"wp-block-list\">\n<li>Impaired mitochondrial dynamics also take down the cell\u2019s cleaning and waste recycling processes, leading to a pileup of toxic proteins that form harmful aggregates inside the cell.\u00a0<\/li>\n\n\n\n<li>In Parkinson\u2019s, the presence of these toxic protein aggregates is a hallmark of the disease.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Parkinson\u2019s Disease<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Parkinson\u2019s Disease (PD) is a <strong>neurodegenerative disorder<\/strong> that disrupts the brain\u2019s ability to produce <strong>dopamine<\/strong>, a vital neurotransmitter responsible for movement control.\n<ul class=\"wp-block-list\">\n<li>PD gets worse over time. There is no cure, but therapies and medicines can reduce symptoms.\u00a0<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Common symptoms include <\/strong>tremors, painful muscle contractions and difficulty speaking.\n<ul class=\"wp-block-list\">\n<li>Parkinson disease results in high rates of disability and the need for care. Many people with PD also develop dementia.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>The disease usually occurs in older people, <\/strong>but younger people can also be affected. Men are affected more often than women.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>In 1817, a British physician named James Parkinson <\/strong>published An Essay on the Shaking Palsy, describing for the first time, cases of a neurodegenerative disorder now known as Parkinson\u2019s disease.\u00a0<\/li>\n\n\n\n<li>Today, Parkinson\u2019s disease is the <strong>second most common neurodegenerative <\/strong>disease in the U.S.\n<ul class=\"wp-block-list\">\n<li>It affects about 1 million Americans and more than 10 million people worldwide.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Parkinson Disease in India<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In India, the <strong>rising life expectancy <\/strong>and growing population are contributing to an increased burden of PD.\u00a0<\/li>\n\n\n\n<li>In contrast to western countries, India grapples with a significant obstacle\u2014PD typically <strong>manifests at a younger age<\/strong>, hitting individuals around 51 years old, roughly a decade earlier.\n<ul class=\"wp-block-list\">\n<li>This early onset has profound implications, impacting individuals during their prime working years.\u00a0<\/li>\n\n\n\n<li>Additionally, the scarcity of neurologists, especially in rural areas, frequently results in <strong>delayed diagnosis and insufficient initial treatment.\u00a0<\/strong><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>The Union health ministry<\/strong> has decided to offer <strong>neurological care at Ayushman Arogya Mandirs<\/strong>, the government&#8217;s primary healthcare centres, to combat the increasing incidence of neurological disorders such as Parkinson&#8217;s, epilepsy and dementia among Indians.<\/li>\n<\/ul>\n\n\n\n<p><strong>Source: <\/strong><a href=\"https:\/\/www.thehindu.com\/sci-tech\/health\/mitochondria-keep-your-brain-cells-alive-%E2%88%92-helping-them-run-smoothly-may-protect-against-parkinsons-disease\/article68585245.ece\" target=\"_blank\" rel=\"noopener\"><strong>TH<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recent research has identified a key protein that could lead to new treatments for Parkinson\u2019s disease and other brain conditions.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[21],"tags":[],"class_list":["post-28867","post","type-post","status-publish","format-standard","hentry","category-current-affairs"],"acf":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/28867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/comments?post=28867"}],"version-history":[{"count":1,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/28867\/revisions"}],"predecessor-version":[{"id":28868,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/posts\/28867\/revisions\/28868"}],"wp:attachment":[{"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/media?parent=28867"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/categories?post=28867"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nextias.com\/ca\/wp-json\/wp\/v2\/tags?post=28867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}